Anthony Varvaro (1-1) hit Eli Whiteside with a pitch to open the 11th before walking Brandon Belt. Chad Durbin replaced Varvaro and struck out Joaquin Arias.
Crawford's homer off Durbin came one pitch after he fouled a ball off his right knee and collapsed to the ground in pain. The left-handed hitting Crawford then pulled the next pitch from Durbin into the right-field seats.
Chipper Jones' second throwing error of the game allowed Justin Christian to reach base. With two outs, Durbin issued an intentional walk to Melky Cabrera before giving up Blanco's homer, also to right field, pushing the Giants' lead to 9-3.